Related Experiment Video
Updated: Feb 24, 2026

05:09
Urethral Stricture Induction Followed by Buccal Mucosa Graft Urethroplasty in a Rat Model
Published on: April 28, 2023
1.6K
[Redo urethroplasty with buccal mucosa]
C M Rosenbaum1, L Ernst2, O Engel2
1Klinik und Poliklinik für Urologie, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Deutschland. c.rosenbaum@uke.de.
Der Urologe. Ausg. A
|August 24, 2017
Summary
Urethral stricture treatments are evolving from less invasive methods to open surgical reconstruction. Redo urethroplasty offers high success and patient satisfaction for recurrent strictures.
Area of Science:
- Urology
- Surgical Reconstruction
Background:
- Urethral strictures significantly impact quality of life, affecting 0.6% of males in industrialized nations.
- Causes include trauma, infection, iatrogenic factors, and idiopathic origins.
- Treatment has shifted towards complex open surgical reconstruction.
Purpose of the Study:
- To review current treatment options for urethral strictures.
- To evaluate success rates and risk factors for recurrence.
- To discuss management strategies for recurrent strictures.
Main Methods:
- Review of current literature on urethral stricture treatment.
- Analysis of success rates for primary and redo urethroplasty.
- Identification of risk factors for stricture recurrence.
Main Results:
- Excision and primary end-to-end anastomosis or buccal mucosa graft urethroplasty achieve >80% success.
- Penile location, stricture length >4 cm, and prior endoscopic therapy are risk factors for recurrence.
- Redo urethroplasty shows high success rates comparable to primary procedures for recurrent strictures.
Conclusions:
- Redo urethroplasty is the preferred choice for recurrent urethral strictures, offering high success and patient satisfaction.
- While primary buccal mucosa grafting has oral morbidity, repeated grafting in redo urethroplasty shows only slightly increased complications.
- Understanding recurrence risk factors guides optimal treatment selection.

