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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

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Persistent post-traumatic headache vs. migraine: an MRI study demonstrating differences in brain structure.

Todd J Schwedt¹, Catherine D Chong^2,3, Jacob Peplinski³

¹Mayo Clinic Arizona, 5777 East Mayo Boulevard, Phoenix, AZ, 85255, USA. Schwedt.todd@mayo.edu.

The Journal of Headache and Pain

|August 24, 2017

Summary

This summary is machine-generated.

Persistent post-traumatic headache and migraine show distinct brain structure differences, suggesting unique underlying causes. Further research is needed to fully understand these headache types.

Keywords:

Brain curvature Brain structure Brain surface area Brain volume Cortical thickness Magnetic resonance imaging Migraine Post-traumatic headache Traumatic brain injury

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Area of Science:

Neuroscience
Neurology
Radiology

Background:

Post-traumatic headache (PTH) symptoms often mimic migraine.
The pathophysiology of PTH remains unclear, with debate on whether it triggers migraine or has unique origins.
This study investigates brain structure differences in persistent PTH after mild traumatic brain injury (mTBI) compared to migraine.

Purpose of the Study:

To compare brain structure in individuals with persistent post-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI) with those experiencing migraine.
To identify specific neuroanatomical differences between these headache conditions.

Main Methods:

Utilized 3T brain MRI scans for 28 individuals with persistent PTH (mTBI-related) and 28 with migraine.
Calculated regional volumes, cortical thickness, surface area, and curvature from T1-weighted MRI sequences.
Employed ANCOVA for group comparisons, with 28 healthy controls for reference.

Main Results:

Identified significant differences in regional brain volumes, cortical thickness, surface area, and curvature between PTH and migraine groups.
Specific structural variations were noted in the right lateral orbitofrontal lobe, left caudal middle frontal lobe, left superior frontal lobe, left precuneus, and right supramarginal gyrus.
PTH group showed structural differences compared to controls in the right lateral orbitofrontal lobe, right supramarginal gyrus, and left superior frontal lobe, unlike the migraine group.

Conclusions:

Persistent post-traumatic headache and migraine exhibit distinct brain structural alterations, suggesting potentially different pathophysiologies.
Further investigation is required to fully elucidate the similarities and differences in brain structure and function between PTH and migraine.
Understanding these neuroanatomical distinctions is crucial for determining the specificity of each headache type.