Nanoparticle-Based Drugs: A Potential Armamentarium of Effective Anti-Cancer Therapies

Khurshid Ahmad1, Gulam Rabbani1, Mohammad Hassan Baig1

  • 1Department of Medical Biotechnology, Yeungnam University, Gyeongsan 38541, Korea.

Current Drug Metabolism
|August 24, 2017
PubMed
Abstract

Insights

Nanoparticles offer targeted cancer therapy, overcoming limitations of traditional treatments. This review explores nanoparticle applications in cancer imaging and treatment, highlighting their potential for future advancements.

Area of Science:

  • Oncology
  • Nanomedicine
  • Biotechnology

Background:

  • Cancer remains a leading global cause of death, with current treatments facing limitations in specificity and biological barrier penetration.
  • Nanoparticles offer enhanced drug delivery efficiency due to their small size and high surface-to-volume ratio, enabling site-specific tumor targeting.
  • The limitations and side effects of conventional therapies drive the investigation of nanotechnological approaches for improved cancer treatment.

Purpose of the Study:

  • To review various cancer therapy approaches and emphasize the critical role of nanoparticles.
  • To discuss the applications and limitations of different nanomedicines in cancer imaging and treatment.
  • To explore the potential of nanotechnology in advancing modern cancer therapies and research strategies.

Main Methods:

  • An extensive literature search was conducted using major bibliographic databases.
  • Keywords and keyword combinations were utilized to retrieve relevant scientific information.
  • The review synthesizes findings on nanoparticle applications in cancer diagnosis and therapy.

Main Results:

  • Nanoparticle-based therapies present a promising avenue for cancer treatment, addressing limitations of conventional methods.
  • Various nanomaterials are employed as nanomedicines for cancer imaging and treatment, each with unique applications and constraints.
  • The review details the integration of nanoparticles into modern cancer therapies and research for improved outcomes.

Conclusions:

  • Nanotechnology has yielded novel therapeutics for cancer diagnosis and treatment over the past decades.
  • Despite advancements, nanotechnological anti-cancer therapies face certain limitations.
  • Nanotechnology is poised to drive significant advancements in nanomedicine and cancer treatment within the next decade.

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