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Updated: Feb 24, 2026

Manufacture and Drug Delivery Applications of Silk Nanoparticles
Published on: October 8, 2016
Nanoparticle-Based Drugs: A Potential Armamentarium of Effective Anti-Cancer Therapies
Khurshid Ahmad1, Gulam Rabbani1, Mohammad Hassan Baig1
1Department of Medical Biotechnology, Yeungnam University, Gyeongsan 38541, Korea.
Background:
Cancer is a foremost cause of mortality worldwide. Available treatments are non-specific and cannot cross biological barriers, which have restricted their usages. Furthermore, the side effects of existing treatments have promoted the exploration of nanotechnological approaches to achieve site-specific drug delivery. The diminutive sizes of nanoparticles, and hence, their large surface to volume ratios, means they are inherently more efficient at delivering drugs to specific tumor sites. This review highlights different approaches to cancer therapy, and the importance of nanoparticles in cancer therapy. Applications and limitations of different types of nanomedicines used for cancer imaging and treatment are discussed.
Methods:
We undertook extensive literature search of bibliographic databases (e.g. PubMed, Google Scholar, Medline, Web of Science etc.) using different keywords and combination of keywords to retrieve the relevant information.
Results:
This review provides overview of cancer and need for nanoparticle-based therapies for their treatment, and deliberates the different types of nanomaterials used as nanomedicines for cancer imaging and treatment in addition to their applications and limitations. Furthermore, applications of nanoparticles in modern cancer therapies and research strategies have been explored to overcome cancer.
Conclusion:
Nanotechnology has provided a lot of novel therapeutics for the diagnosis and treatment of different cancers over the last 2-3 decades. However, there are few limitations of nanotechnological based anti-cancer therapies. Nanotechnology is enabling novel, specialized treatments for cancer; this will be a high-impact area of nanomedicine yielding more medical advancements with the next 10 years.
Insights
Nanoparticles offer targeted cancer therapy, overcoming limitations of traditional treatments. This review explores nanoparticle applications in cancer imaging and treatment, highlighting their potential for future advancements.
Area of Science:
- Oncology
- Nanomedicine
- Biotechnology
Background:
- Cancer remains a leading global cause of death, with current treatments facing limitations in specificity and biological barrier penetration.
- Nanoparticles offer enhanced drug delivery efficiency due to their small size and high surface-to-volume ratio, enabling site-specific tumor targeting.
- The limitations and side effects of conventional therapies drive the investigation of nanotechnological approaches for improved cancer treatment.
Purpose of the Study:
- To review various cancer therapy approaches and emphasize the critical role of nanoparticles.
- To discuss the applications and limitations of different nanomedicines in cancer imaging and treatment.
- To explore the potential of nanotechnology in advancing modern cancer therapies and research strategies.
Main Methods:
- An extensive literature search was conducted using major bibliographic databases.
- Keywords and keyword combinations were utilized to retrieve relevant scientific information.
- The review synthesizes findings on nanoparticle applications in cancer diagnosis and therapy.
Main Results:
- Nanoparticle-based therapies present a promising avenue for cancer treatment, addressing limitations of conventional methods.
- Various nanomaterials are employed as nanomedicines for cancer imaging and treatment, each with unique applications and constraints.
- The review details the integration of nanoparticles into modern cancer therapies and research for improved outcomes.
Conclusions:
- Nanotechnology has yielded novel therapeutics for cancer diagnosis and treatment over the past decades.
- Despite advancements, nanotechnological anti-cancer therapies face certain limitations.
- Nanotechnology is poised to drive significant advancements in nanomedicine and cancer treatment within the next decade.
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