Air pollution and low birth weight in an industrialized city in Southeastern Brazil, 2003-2006
Marcelo Moreno Dos Reis1,2, Mariana Tavares Guimarães1, Alfésio Luís Ferreira Braga1,3
1Laboratory of Experimental Atmospheric Pollution, Pathology Department, School of Medicine, Universidade de São Paulo - São Paulo (SP), Brazil.
Insights
Air pollution, specifically PM10 and ozone (O3), is linked to an increased risk of low birth weight (LBW) in newborns. Exposure during pregnancy, even below Brazilian air quality standards, poses risks to fetal development.
Area of Science:
- Environmental Health
- Reproductive Health
- Pediatrics
Background:
- Birth weight is a critical indicator of infant health and long-term well-being.
- Air pollution exposure during pregnancy is increasingly recognized as a risk factor for adverse birth outcomes.
Purpose of the Study:
- To investigate the association between maternal exposure to air pollutants and low birth weight (LBW) in Volta Redonda, Brazil.
- To quantify the risk of LBW associated with specific air pollutants (PM10 and O3) during different trimesters of pregnancy.
Main Methods:
- Retrospective cohort study utilizing birth data from the Brazilian Information System (2003-2006).
- Maternal exposure to O3, PM10, temperature, and humidity assessed using data from the Governmental Air Quality Monitoring System.
- Statistical models (Linear and Logistic) adjusted for multiple covariates including maternal and infant characteristics, and weather variables.
Main Results:
- Low birth weight (LBW) accounted for 9.1% of 13,660 newborns.
- Increased exposure to PM10 in the second and third trimesters was associated with higher odds of LBW (OR=1.06).
- Ozone (O3) exposure in the second and third trimesters also increased LBW odds (OR=1.03) and was linked to a 31.11g reduction in birth weight in the third trimester.
Conclusions:
- Maternal exposure to PM10 and O3, even below established air quality standards, increases the risk of low birth weight.
- Findings highlight the need for stricter air quality regulations to protect fetal health.
- This study underscores the importance of monitoring and mitigating air pollution for improved pregnancy outcomes.
Introduction::
Birth weight is an important indicator of several conditions that manifest earlier (as fetal and neonatal mortality and morbidity, inhibited growth and cognitive development) and later in life such as chronic diseases. Air pollution has been associated with adverse pregnancy outcomes.
Objective::
Retrospective cohort study investigated the association between low birth weight (LBW) and maternal exposure to air pollutants in Volta Redonda city, Rio de Janeiro, Brazil, from 2003 to 2006.
Methods::
Birth data was obtained from Brazilian Information System. Exposure information (O3, PM10, temperature and humidity) was provided by Governmental Air Quality Monitoring System. Linear and Logistic models, adjusted for sex, type of pregnancy, prenatal care, place of birth, maternal age, parity, education, congenital anomalies and weather variables were employed.
Results::
Low birth weight (LBW) represented 9.1% of all newborns (13,660). For an interquartile range increase in PM10 it was found OR2 ndTrimester = 1.06 (95%CI 1.02 - 1.10), OR3 rdTrimester = 1.06 (95%CI 1.02 - 1.10) and, in O3 it was found OR2 ndTrimester = 1.03 (95%CI 1.01 - 1.04), OR3 rdTrimester = 1.03 (95%CI 1.02 - 1.04). The dose-response relationship and a reduction in birth weight of 31.11 g (95%CI -56.64 - -5.58) was observed in the third trimester of pregnancy due to an interquartile increase of O3.
Conclusion::
This study suggests that exposures to PM10 and O3, even being below the Brazilian air quality standards, contribute to risks of low birth weight.
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