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Related Experiment Video

Updated: Feb 24, 2026

Modified Posterior Vertebral Column Resection for Patients with Thoracolumbar Kyphotic Deformity
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Thoracic Kyphosis and Physical Function: The Framingham Study.

Amanda L Lorbergs1,2,3, Joanne M Murabito4,5,6, Mohamed Jarraya7

  • 1Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts.

Journal of the American Geriatrics Society
|August 24, 2017
PubMed
Summary
This summary is machine-generated.

Thoracic kyphosis, a measure of spinal curvature, did not predict future physical function in healthy adults. Measuring spinal curvature alone is insufficient to identify individuals at risk for functional decline.

Keywords:
agingepidemiologymobilityphysical functionthoracic curvature

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Area of Science:

  • Gerontology and Rehabilitation Medicine
  • Biomedical Imaging and Diagnostics
  • Epidemiology and Biostatistics

Background:

  • Thoracic kyphosis, an outward curvature of the thoracic spine, is common and can increase with age.
  • The relationship between thoracic kyphosis severity and subsequent physical function remains incompletely understood.
  • Previous studies have yielded conflicting results regarding the impact of kyphosis on physical performance.

Purpose of the Study:

  • To investigate the prospective association between thoracic kyphosis, measured via computed tomography (CT), and various measures of physical function.
  • To determine if kyphosis severity predicts declines in walking speed, chair-stand ability, grip strength, or self-reported function.
  • To examine these associations across different age groups and sexes.

Main Methods:

  • A prospective cohort study of 1,100 participants from the Framingham Heart Study (Offspring and Third Generation cohorts) was analyzed.
  • Thoracic kyphosis (T4-T12 Cobb angle) was quantified using supine CT scout images.
  • Physical function (walking speed, chair-stand time, grip strength, self-reported impairments) was assessed a mean of 3.4 years later and adjusted for covariates.

Main Results:

  • No significant association was found between thoracic kyphosis severity and any physical function measures in men or women.
  • These findings were consistent across age strata (younger than 65 and 65 and older).
  • For instance, walking speed did not differ between participants in the highest quartile of kyphosis and those in the lower quartiles.

Conclusions:

  • In a cohort of relatively healthy, high-functioning individuals, thoracic kyphosis severity, as measured by supine CT, does not predict subsequent physical function.
  • Current supine CT measures of thoracic curvature alone are not adequate for identifying individuals at risk of future functional decline.
  • Further research may be needed to identify other biomarkers or clinical factors associated with functional decline.