Related Experiment Video
Updated: Feb 24, 2026
07:15
Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
12.4K
Association between periodontitis and severe asthma in adults: A case-control study
Kaliane Rocha Soledade-Marques1, Isaac Suzart Gomes-Filho1, Simone Seixas da Cruz1,2
1Department of Health, Feira de Santana State University, Feira de Santana Bahia, Brazil.
Oral Diseases
|August 24, 2017
Summary
Periodontitis, a gum disease, is associated with a threefold increased risk of severe asthma. Further research is needed to understand the causal link between these conditions.
Area of Science:
- Oral health
- Respiratory medicine
- Immunopathology
Background:
- Severe asthma affects millions globally, with complex underlying mechanisms.
- Periodontitis is a common inflammatory condition affecting the gums and supporting structures of teeth.
Purpose of the Study:
- To investigate the potential association between periodontitis and severe asthma.
- To determine if periodontitis increases the risk of developing severe asthma.
Main Methods:
- A case-control study compared 130 adults with severe asthma to 130 adults without asthma.
- Periodontitis was defined by specific criteria including probing depth, clinical attachment level, and bleeding on probing.
- Severe asthma diagnosis followed Global Initiative for Asthma guidelines.
Main Results:
- An association was found between periodontitis and severe asthma (OR crude = 2.98, OR adjusted = 3.01-3.25).
- Individuals with periodontitis had approximately a threefold higher risk of severe asthma.
- The prevalence of periodontitis was significantly higher in the severe asthma group (46.6%) compared to the control group (22.3%).
Conclusions:
- A significant association exists between periodontitis and severe asthma.
- The directionality of this relationship requires further investigation.
- Potential links include causality, asthma's immunopathology, or medication side effects.
Related Concept Videos
01:29Asthma-I: Introduction
3.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.6K
01:24Asthma-III: Symptoms and Complications
3.4K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
3.4K
01:26Asthma-II: Pathophysiology and Classification
4.6K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.6K
01:20Asthma: Pathogenesis and Management
1.5K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.5K
01:30Asthma-IV: Diagnostic and Management
3.2K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.2K
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
4.9K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
4.9K