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Related Experiment Videos

Who needs molar units for drugs?

L F Prescott, A T Proudfoot, B Widdop

    Lancet (London, England)
    |May 16, 1987
    PubMed
    Summary

    Standardizing drug concentration measurement in clinical settings is crucial. Mass units are recommended over molar units to prevent patient harm, disruption, and unnecessary costs associated with changing prescription practices.

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    Area of Science:

    • Clinical pharmacology
    • Pharmaceutical science
    • Medical laboratory science

    Background:

    • Current drug concentration measurements in clinical medicine lack standardization.
    • The need for a unified system to ensure patient safety and treatment efficacy is critical.

    Purpose of the Study:

    • To evaluate the necessity and feasibility of standardizing drug concentration units in clinical medicine.
    • To assess the implications of adopting molar units versus retaining mass units for drug measurements.

    Main Methods:

    • Literature review and critical analysis of current practices in drug concentration measurement.
    • Evaluation of the potential impact of unit standardization on clinical workflows, patient safety, and economic factors.

    Main Results:

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    • Mass units (e.g., mg/L) are deemed the most practical and safe choice for drug concentration measurement.
    • Transitioning to molar units would introduce significant disruption, inconvenience, and potential patient danger.
    • There is no clear benefit for clinicians or patients in adopting molar units for drugs.

    Conclusions:

    • Mass units should be retained for drug concentration measurements in clinical medicine.
    • Proposals for adopting molar units should be abandoned due to lack of benefit and potential risks.
    • Standardization using mass units is essential for safe and effective clinical practice.