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Topical flurbiprofen toxicosis in a cat.
Elizabeth M Yi1, Elizabeth Leech1
1VCA Emergency Animal Hospital and Referral Center, San Diego, CA, 92108.
Summary
A cat developed severe illness, including anemia and gastrointestinal bleeding, after topical exposure to flurbiprofen cream. This case highlights the dangers of non-steroidal anti-inflammatory drug toxicosis in pets.
Area of Science:
- Veterinary Toxicology
- Small Animal Internal Medicine
Background:
- Topical non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used for pain relief.
- Accidental exposure in pets can lead to severe toxicity, but data in cats is limited.
Observation:
- A 3-year-old domestic shorthair cat presented with lethargy, vomiting, and anemia following likely exposure to a topical flurbiprofen cream.
- Clinical signs included severe azotemia, intractable anemia requiring transfusions, and gastric ulcerations with duodenal perforation.
Findings:
- The cat required extensive supportive care, including multiple blood transfusions, fluid therapy, and gastrointestinal medications.
- Surgical intervention for duodenal perforation was necessary, after which the cat's azotemia and anemia resolved.
- Flurbiprofen exposure was confirmed via urine toxicology analysis.
Implications:
- This case represents the first documented instance of flurbiprofen toxicosis in a cat resulting from topical cream exposure.
- Highlights the potential for severe adverse effects from NSAIDs applied topically, even in small domestic animals.
- Emphasizes the need for heightened owner awareness regarding the safe storage and use of topical medications around pets.
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