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Cerebral venous sinus thrombosis in homocystinuria: Dietary intervention in conjunction with anticoagulation

Sufin Yap1, Deborah Annesley-Williams2,3, Orla Hardiman4,5

  • 1Department of Inherited Metabolic Diseases, Sheffield Children's NHS Foundation Trust, Sheffield, UK.

SAGE Open Medical Case Reports
|August 25, 2017
PubMed

Insights

Cerebral venous sinus thrombosis (CVST) can present acutely or chronically. Early anticoagulation and dietary changes in a homocystinuria patient led to a favorable outcome in this case.

Area of Science:

  • Neurology
  • Vascular Medicine
  • Genetics

Background:

  • Cerebral venous sinus thrombosis (CVST) presents variably, posing diagnostic challenges.
  • CVST is an uncommon complication of homocystinuria, a metabolic disorder.

Observation:

  • A case of CVST in a patient with homocystinuria is presented.
  • The patient experienced both acute and chronic symptoms.

Findings:

  • Early anticoagulation therapy was initiated.
  • Dietary intervention was implemented concurrently.
  • These interventions were associated with a positive clinical outcome.

Implications:

  • Highlights the importance of considering CVST in homocystinuria.
  • Suggests that prompt anticoagulation and dietary management can improve prognosis.
  • Emphasizes the need for early diagnosis and intervention in complex cases.

Keywords:
Homocystinuriaanticoagulationdietary treatmentsuperior sagittal sinus thrombosis

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