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Atrial Fibrillation and Anticoagulation in Hypertrophic Cardiomyopathy

C Fielder Camm1, A John Camm2,3

  • 1University of Oxford, Oxford.

Arrhythmia & Electrophysiology Review
|August 25, 2017
PubMed

Insights

Hypertrophic cardiomyopathy (HCM) is linked to atrial fibrillation (AF). Patients with HCM and AF face increased stroke risk, necessitating careful anticoagulation management.

Area of Science:

  • Cardiology
  • Genetics
  • Electrophysiology

Background:

  • Hypertrophic cardiomyopathy (HCM) is a prevalent inherited cardiac condition.
  • HCM is associated with serious complications like stroke and sudden cardiac death.
  • A significant link exists between HCM and the development of atrial fibrillation (AF).

Purpose of the Study:

  • To review the epidemiology of AF in patients with HCM.
  • To analyze risk factors contributing to AF development in this population.
  • To discuss outcomes of AF in HCM patients and anticoagulation strategies.

Main Methods:

  • Literature review focusing on AF in HCM.
  • Epidemiological analysis of AF prevalence and risk factors.
  • Evaluation of stroke risk and anticoagulation evidence.

Main Results:

  • AF is a recognized complication within the HCM population.
  • Patients with HCM and AF exhibit a higher stroke risk than the general AF population.
  • Specific risk factors for AF development in HCM are identified.

Conclusions:

  • AF is common in HCM and elevates stroke risk.
  • Anticoagulation strategies are crucial for managing HCM patients with AF.
  • Further research into optimal anticoagulation is warranted.

Keywords:
Hypertrophic cardiomyopathyanticoagulationatrial fibrillationstroke

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