Bilateral macular infarction after gemcitabine and carboplatin chemotherapy
Umesh Chandra Behera1, Rohit R Modi2, Jenil Sheth2
1L V Prasad Eye Institute, Patia, Bhubaneswar, Odisha, 751024, India. umeshcbehera@gmail.com.
Purpose:
To report a case of macular infarction after doublet chemotherapy with gemcitabine and carboplatin.
Methods:
A middle-aged lady presenting with bilateral macular infarction post-chemotherapy for metastatic cervical malignancy was investigated for thromboembolic risks and treated.
Results:
The macular perfusion and edema improved with control of hypertension and treatment with pentoxifylline. Visual improvement was satisfactory, and the possible associated risk such as hypertension was noted.
Conclusion:
This case underscores the need for active screening of patients on chemotherapy with gemcitabine and carboplatin for retinal vascular occlusive changes when hypertension is associated.
