Related Experiment Videos
A partially rigid butyrophenone analog with extended conformation
Die Pharmazie
|December 1, 1986
Abstract:
The synthesis and in vitro dopamine D2 receptor binding of a conformationally restricted analog of 4-piperidinobutyrophenone is described. 2-(2-Piperidinoethyl)-1-tetralone displaces [3H]spiperone from the rat striatal dopamine receptor with an IC50 of 1.2 X 10(-4)mol/l.