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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

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Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
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Mitral Regurgitation III: Medical Management01:25

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Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
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Mitral Stenosis I: Introduction01:22

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Mitral Valve Prolapse I: Introduction01:27

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IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
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Mitral Valve Prolapse II: Assessment and Management01:22

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IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
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Mitral Valve Prolapse III: Nursing Management01:19

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The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
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Transcatheter Mitral Valve Implantation Using the HighLife System.

Marco Barbanti1, Nicolò Piazza2, Sarah Mangiafico1

  • 1Ferrarotto Hospital, University of Catania, Catania, Italy.

JACC. Cardiovascular Interventions
|August 26, 2017
PubMed
Summary
This summary is machine-generated.

The HighLife transcatheter mitral valve system shows technical feasibility and safety for mitral regurgitation treatment. Early results demonstrate excellent hemodynamic performance in initial human implantations.

Keywords:
mitral regurgitationprosthesistranscatheter mitral valve replacement

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Area of Science:

  • Cardiovascular Surgery
  • Interventional Cardiology
  • Biomedical Engineering

Background:

  • Transcatheter mitral valve implantation offers a promising solution for mitral regurgitation in high-risk patients.
  • The HighLife system is a novel 2-component device designed for mitral valve replacement.
  • Severe mitral regurgitation often occurs in patients with comorbidities and reduced left ventricular function.

Observation:

  • The first human implantations of the HighLife system were performed in two patients with severe functional mitral regurgitation.
  • Procedures involved transfemoral deployment of the subannular implant and transapical release of the mitral valve.
  • Both patients were hemodynamically stable intraoperatively with no major complications.

Findings:

  • Post-procedure echocardiograms revealed excellent prosthetic valve function, low gradients, and no paravalvular leaks.
  • One patient survived 5 months with improved functional class, while the other experienced rapid left ventricular deterioration post-procedure.
  • Mild intraprosthetic regurgitation was noted in both cases.

Implications:

  • The HighLife system is technically feasible and safe for transcatheter mitral valve implantation.
  • Early hemodynamic outcomes suggest favorable prosthesis performance.
  • Further investigation is warranted to optimize patient selection and management for this innovative transcatheter approach.