Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

499
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
499
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

345
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
345
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

421
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
421
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

828
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
828

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spontaneous Myocardial Infarction After Left Main Revascularization: The EXCEL Trial.

Circulation·2026
Same author

Editorial: Do less, do better? Challenging the concomitant PCI paradigm in TAVR.

Cardiovascular revascularization medicine : including molecular interventions·2025
Same author

Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients With Left Main Disease With and Without Diabetes: Findings From a Pooled Analysis of 4 Randomized Clinical Trials.

Circulation·2024
Same author

Percutaneous Coronary Intervention vs Coronary Artery Bypass Graft Surgery for Left Main Disease in Patients With and Without Acute Coronary Syndromes: A Pooled Analysis of 4 Randomized Clinical Trials.

JAMA cardiology·2023
Same author

Comparative study of male and female patients undergoing surgical aortic valve replacement.

Interdisciplinary cardiovascular and thoracic surgery·2023
Same author

Impact of Periprocedural Adverse Events After PCI and CABG on 5-Year Mortality: The EXCEL Trial.

JACC. Cardiovascular interventions·2023

Related Experiment Video

Updated: Feb 24, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
06:04

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Published on: August 8, 2025

647

Long-term outlook for transcatheter aortic valve replacement.

Andras P Durko1, Ruben L Osnabrugge1, A Pieter Kappetein1

  • 1Department of Cardio-Thoracic Surgery, Erasmus University Medical Center Rotterdam, Thoraxcentrum, s'-Gravendijkwal 230, 3015CE, Rotterdam, The Netherlands.

Trends in Cardiovascular Medicine
|August 26, 2017
PubMed
Summary

Transcatheter aortic valve replacement (TAVR) offers a new option for severe symptomatic aortic stenosis (AS). This review explores TAVR's future, challenges, and comparison with surgical valve replacement.

Keywords:
ComplicationsDurabilityFuture outlookTAVITAVR, transcatheter aortic valve implantationTranscatheter aortic valve replacement

More Related Videos

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
05:31

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Published on: June 8, 2022

3.4K
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.9K

Related Experiment Videos

Last Updated: Feb 24, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
06:04

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Published on: August 8, 2025

647
Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
05:31

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Published on: June 8, 2022

3.4K
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.9K

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Severe symptomatic aortic stenosis (AS) treatment has been transformed by transcatheter aortic valve replacement (TAVR).
  • TAVR is now being considered for increasingly lower-risk patient populations.
  • The long-term implications and optimal positioning of TAVR in AS management remain under investigation.

Purpose of the Study:

  • To review the long-term outlook for transcatheter aortic valve replacement (TAVR).
  • To discuss the challenges associated with TAVR procedures.
  • To examine the relationship between TAVR and conventional surgical aortic valve replacement (SAVR).

Main Methods:

  • Literature review of current studies and clinical trials on TAVR and SAVR.
  • Analysis of long-term outcomes, safety, and efficacy data for both procedures.
  • Comparative assessment of TAVR and SAVR in various patient risk groups.

Main Results:

  • TAVR has demonstrated significant benefits, particularly in high-risk patients, and is expanding to lower-risk groups.
  • Long-term durability and potential complications of TAVR valves require ongoing monitoring.
  • Patient selection and procedural techniques continue to evolve, impacting outcomes.

Conclusions:

  • TAVR has a promising future in managing aortic stenosis, but its role relative to SAVR needs further clarification.
  • Addressing TAVR's long-term challenges is crucial for its sustained success.
  • Future research should focus on comparative effectiveness and optimal patient stratification for TAVR versus SAVR.