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Published on: January 30, 2020
A comparison of pediatric airway management techniques during out-of-hospital cardiac arrest using the CARES database
Matthew L Hansen1, Amber Lin1, Carl Eriksson2
1Center for Policy and Research in Emergency Medicine, Oregon Health & Science University, United States.
Insights
Bag-valve-mask ventilation (BVM) showed higher survival rates for pediatric out-of-hospital cardiac arrest (OHCA) patients compared to supraglottic airway (SGA) and endotracheal intubation (ETI). Further research is recommended to confirm these findings in OHCA survival outcomes.
Area of Science:
- Pediatric Emergency Medicine
- Cardiovascular Research
- Resuscitation Science
Background:
- Out-of-hospital cardiac arrest (OHCA) in children presents unique challenges.
- Airway management is a critical component of pediatric resuscitation.
- Comparing different airway strategies is essential for improving survival rates.
Purpose of the Study:
- To compare the odds of survival to hospital discharge among pediatric OHCA patients.
- To evaluate the effectiveness of bag-valve-mask ventilation (BVM), supraglottic airway (SGA), and endotracheal intubation (ETI).
- To adjust for the propensity of receiving a specific airway intervention.
Main Methods:
- Retrospective cohort study utilizing the Cardiac Arrest Registry to Enhance Survival (CARES) database (2011-2015).
- Inclusion of pediatric patients (<18 years) with non-traumatic OHCA receiving Emergency Medical Services (EMS) resuscitation.
- Propensity score analysis to compare survival outcomes for BVM, ETI, and SGA.
Main Results:
- Analysis included 1724 pediatric OHCA cases from EMS agencies using all three airway devices.
- Bag-valve-mask ventilation (BVM) was associated with higher survival to hospital discharge compared to endotracheal intubation (ETI) (OR 0.39) and supraglottic airway (SGA) (OR 0.32).
- Findings were robust across sensitivity analyses, including complete case, EMS-agency matched, and age-stratified analyses.
Conclusions:
- Bag-valve-mask ventilation (BVM) demonstrated a statistically significant association with higher survival to hospital discharge in pediatric OHCA patients compared to ETI and SGA.
- The study highlights potential differences in airway management effectiveness for pediatric OHCA.
- A large-scale randomized clinical trial is warranted to definitively confirm these findings and guide clinical practice.
Objective:
To compare odds of survival to hospital discharge among pediatric out-of-hospital cardiac arrest (OHCA) patients receiving either bag-valve-mask ventilation (BVM), supraglottic airway (SGA) or endotracheal intubation (ETI), after adjusting for the propensity to receive a given airway intervention.
Methods:
Retrospective cohort study using the Cardiac Arrest Registry to Enhance Survival (CARES) database from January 1 201-December 31, 2015. The CARES registry includes data on cardiac arrests from 17 statewide registries and approximately 55 additional US cities. We included patients less than18 years of age who suffered a non-traumatic OHCA and received a resuscitation attempt by Emergency Medical Services (EMS). The key exposure was the airway management strategy (BVM, ETI, or SGA). The primary outcome was survival to hospital discharge.
Results:
Of the 3793 OHCA cases included from 405 EMS agencies, 1724 cases were analyzed after limiting the analysis to EMS agencies that used all 3 devices. Of the 1724, 781 (45.3%) were treated with BVM only, 727 (42.2%) ETI, and 215 (12.5%) SGA. Overall, 20.7% had ROSC and 10.9% survived to hospital discharge. After using a propensity score analysis, the odds ratio for survival to hospital discharge for ETI compared to BVM was 0.39 (95%CI 0.26-0.59) and for SGA compared to BVM was 0.32 (95% CI 0.12-0.84). These relationships were robust to the sensitivity analyses including complete case, EMS-agency matched, and age-stratified.
Conclusions:
BVM was associated with higher survival to hospital discharge compared to ETI and SGA. A large randomized clinical trial is needed to confirm these findings.
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