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Racial Difference in Cerebral Microbleed Burden among Ischemic Stroke Patients

Shima Shahjouei1, Georgios Tsivgoulis2, Mantinderpreet Singh3

  • 1Department of Neurology, University of Tennessee Health Science Center, Memphis, Tennessee; Universal Scientific Education and Research Network (USERN), Tehran, Iran.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
|August 26, 2017
PubMed
Abstract

Insights

Cerebral microbleeds (CMBs) prevalence and location did not differ between African American and Caucasian stroke patients. However, African Americans may have a higher prevalence of multiple CMBs (≥5).

Area of Science:

  • Neurology
  • Radiology
  • Epidemiology

Background:

  • Limited data exists on the epidemiology of cerebral microbleeds (CMBs) in ischemic stroke patients.
  • Cerebral microbleeds are small spots of bleeding in the brain, often detected using MRI.
  • Understanding CMBs is crucial for stroke risk assessment and management.

Purpose of the Study:

  • To compare the number, associated factors, and topography of CMBs between African American and Caucasian ischemic stroke patients.
  • To investigate racial disparities in CMBs within the Mid-South United States population.
  • To contribute to the limited epidemiological data on CMBs in stroke patients.

Main Methods:

  • Retrospective analysis of consecutive ischemic stroke patients at a tertiary stroke center.
  • Evaluation of T2*-weighted magnetic resonance images for CMBs (number, location, topography).
  • Analysis of demographic and clinical data, including hypertension and diabetes mellitus prevalence.

Main Results:

  • No significant difference in CMB presence or location between African Americans and Caucasians.
  • African Americans were younger and had higher rates of hypertension and diabetes.
  • A trend towards a higher number of CMBs in African Americans, with a significantly higher likelihood of having 5 or more CMBs.

Conclusions:

  • No observed racial differences in the presence, number, or location of cerebral microbleeds.
  • Findings suggest a potentially higher prevalence of multiple CMBs (≥5) among African American stroke patients.
  • Further research is warranted to elucidate the underlying mechanisms and clinical implications of these findings.
Keywords:
Cerebral microbleedscerebral small vessel diseaseepidemiologyethnicityischemic stroke

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