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Updated: Feb 24, 2026

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Capsule endoscopy: 10 years on and in the frontline
M E McAlindon1, D S Sanders1, R Sidhu1
1Small Bowel and Nutrition Unit, Department of Gastroenterology, Royal Hallamshire Hospital, Sheffield, UK.
Abstract:
Capsule endoscopy is a safe, simple, remote method of visualising the gastrointestinal tract without resorting to conventional endoscopic intubation or radiation exposure. In addition, the ability to visualise the small bowel mucosa directly means that it is considerably more sensitive than existing small bowel imaging modalities in detecting subtle abnormalities. It is a firstline investigative modality for suspected small bowel bleeding and is being increasingly used for detecting evidence of other small bowel diseases. In Crohn's disease, it can confirm evidence of activity without recourse to repeated endoscopic intubation or radiation but does not replace MRI and CT which are better suited to defining stricturing disease and transmural complications. The production of different capsule endoscopes to examine the oesophagus, small bowel and colon now means that almost all of the gut can be examined using this technology.
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