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Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents01:18

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

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Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

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Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
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Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents01:20

Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents

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Diarrhea is characterized by the occurrence of frequent, watery bowel movements. Various factors can trigger diarrhea, including viral or bacterial infections, foodborne illnesses, side effects from certain medications, and underlying digestive disorders. If not adequately managed, diarrhea can lead to complications such as dehydration, electrolyte imbalances, and nutrient deficiencies. Severe diarrhea can lead to significant weight loss, malnutrition, and weakened immune function.
Adsorbents...
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Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents01:17

Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents

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Diarrhea, a condition marked by frequent loose or watery bowel movements, can be triggered by multiple factors such as viral or bacterial infections, food intolerances, anxiety, medications, and digestive disorders. Symptoms may include abdominal pain, bloating, nausea, and cramping. Severe or prolonged diarrhea can lead to complications like electrolyte imbalances, malnutrition, and dehydration if left untreated.
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
754
Enteral Nutrition I: Orogastric and Nasogastric Feeding01:26

Enteral Nutrition I: Orogastric and Nasogastric Feeding

1.8K
Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
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Enteral tube feeding in adults.

The journal of the Royal College of Physicians of Edinburgh·2015
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The effects of bolus and continuous nasogastric feeding on gastro-oesophageal reflux and gastric emptying in healthy volunteers: a randomised three-way cross-over study.

The Proceedings of the Nutrition Society·2008
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Enteral nutrition.

Hospital medicine (London, England : 1998)·2004
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Availability of fully staffed GI endoscopy lists at the weekend for inpatients: does it make a difference?

Clinical medicine (London, England)·2003
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Distal colonic motor activity in four subgroups of patients with irritable bowel syndrome.

Digestive diseases and sciences·2002
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Changes in parenteral nutrition supply when the nutrition support team controls prescribing.

Nutrition (Burbank, Los Angeles County, Calif.)·2001
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Related Experiment Video

Updated: Feb 24, 2026

Author Spotlight: Exploring Non-Pharmacological Therapies for Chronic Respiratory Diseases — Linking Intestinal Microbiome Insights to COPD Treatment
03:25

Author Spotlight: Exploring Non-Pharmacological Therapies for Chronic Respiratory Diseases — Linking Intestinal Microbiome Insights to COPD Treatment

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Diarrhoea in the enterally fed patient.

T E Bowling

    Frontline Gastroenterology
    |August 26, 2017
    PubMed
    Summary

    Diarrhoea from enteral feeding is common, often linked to antibiotics. Management involves adjusting medications, treating other conditions, and sometimes changing feeding methods to control symptoms.

    Area of Science:

    • Gastroenterology
    • Clinical Nutrition
    • Pharmacology

    Background:

    • Diarrhoea is a frequent complication of enteral feeding across clinical settings.
    • Concomitant antibiotic use is identified as a primary risk factor for this condition.
    • Mechanisms involve colonic flora changes and feed delivery responses, but in vivo understanding is limited.

    Purpose of the Study:

    • To summarize the common causes and management strategies for diarrhoea associated with enteral feeding.
    • To highlight the role of antibiotics and feeding methods in the development of this complication.

    Main Methods:

    • Literature review and clinical observation synthesis.
    • Analysis of risk factors, underlying mechanisms, and treatment options.

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    Main Results:

    • Antibiotics significantly increase the risk of enteral feeding-associated diarrhoea.
    • Alterations in gut microbiota and feeding delivery methods are key factors.
    • Management strategies include medication review, comorbidity assessment, and antidiarrhoeal agents.

    Conclusions:

    • Effective management requires a multi-faceted approach addressing medications, patient comorbidities, and feeding protocols.
    • Further research is needed to fully elucidate the in vivo mechanisms of this common clinical issue.