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An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
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Endoscopic Studies I: Bronchoscopy and Thoracoscopy01:30

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Transnasal endoscopy: no gagging no panic!

Clare Parker1, Estratios Alexandridis2, John Plevris3

  • 1South Tyneside NHS Foundation Trust, South Tyneside District Hospital, South Shields, UK.

Frontline Gastroenterology
|August 26, 2017
PubMed
Summary

Transnasal endoscopy (TNE) is well-tolerated and effective for diagnosing upper gastrointestinal issues. While accurate for many conditions, further research is needed for early gastric cancer detection.

Keywords:
BARRETT'S OESOPHAGUSDIAGNOSTIC AND THERAPEUTIC ENDOSCOPYENDOSCOPYGASTRIC CANCEROESOPHAGEAL VARICES

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Area of Science:

  • Gastroenterology
  • Endoscopic Procedures
  • Otolaryngology

Background:

  • Transnasal endoscopy (TNE) utilizes an ultrathin endoscope inserted via the nasal passages.
  • TNE is increasingly adopted for various diagnostic and therapeutic applications.
  • This review synthesizes technical aspects, tolerability, safety, and clinical utility of TNE.

Purpose of the Study:

  • To review the technical characteristics, tolerability, safety, and acceptability of TNE.
  • To evaluate the diagnostic accuracy, screening potential, and therapeutic applications of TNE.
  • To provide practical guidance for optimizing TNE practice and managing complications.

Main Methods:

  • A comprehensive Medline search was conducted.
  • Keywords included "transnasal", "ultrathin", "small calibre", "endoscopy", and "EGD" to identify relevant literature.

Main Results:

  • TNE demonstrates superior tolerability compared to standard endoscopy, with nasal discomfort being the primary manageable issue.
  • Diagnostic yield for Barrett's oesophagus, gastric cancer, and GORD-related diseases is comparable to standard endoscopy.
  • TNE is safe and feasible for primary care screening, beneficial for the elderly and those with comorbidities, and advantageous for specific therapeutic interventions.

Conclusions:

  • Transnasal endoscopy is a well-tolerated and valuable diagnostic tool for upper gastrointestinal pathology.
  • Further evidence is necessary to confirm TNE's accuracy in diagnosing small, early gastric malignancies.
  • TNE shows emerging potential in therapeutic endoscopy, warranting additional investigation.