Magnetic ionic liquid assisted single-drop microextraction of ascorbic acid before its voltammetric determination

Area of Science:

• Analytical Chemistry
• Electrochemistry
• Materials Science

Background:

• Ascorbic acid (vitamin C) is a crucial biomolecule with significant health implications.
• Accurate quantification of ascorbic acid is essential for nutritional analysis and quality control.
• Existing analytical methods may require complex procedures or lack sensitivity.

Purpose of the Study:

• To develop and validate a novel analytical method for ascorbic acid determination.
• To couple microextraction using a magnetic ionic liquid with voltammetric analysis.
• To assess the method's applicability in real-world samples.

Main Methods:

• Synthesis of a hydrophobic magnetic ionic liquid (aliquat tetrachloromanganate(II)).
• Single-drop microextraction of ascorbic acid from aqueous solutions.
• Voltammetric determination using a carbon paste electrode modified with TiO2 nanoparticles.

Main Results:

• A linear concentration range of 1.50-40.0 nM for ascorbic acid was achieved.
• A low detection limit of 0.43 nM was obtained.
• The method demonstrated successful application in analyzing vitamin C effervescent tablets and orange juice.

Conclusions:

• The developed method provides a sensitive and efficient approach for ascorbic acid quantification.
• The combination of magnetic ionic liquid microextraction and voltammetry offers a promising analytical tool.
• This technique is suitable for the analysis of ascorbic acid in complex matrices like food and pharmaceutical products.