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Eyelid Merkel cell carcinoma in a patient treated with golimumab
H Hanafi1, R M Verdijk2, D Paridaens1
1a Department of Oculoplastic & Orbital Surgery , The Rotterdam Eye Hospital , Rotterdam , The Netherlands.
Purpose:
To describe a clinical case of biopsy-proven Merkel cell carcinoma of the eyelid following golimumab therapy for rheumatoid arthritis (RA).
Methods:
Interventional case report.
Results:
A 73-year-old woman with a history of chronic RA presented with a right upper eyelid mass. She had been treated with golimumab (tumor necrosis factor (TNF) inhibitors) injection therapy for the past 6 months. A biopsy showed findings suggestive of a Merkel cell carcinoma of the eyelid.
Conclusions:
Merkel cell carcinoma may be associated with anti-TNF treatment and should be included in the differential diagnosis of an eyelid tumor in patients treated with TNF inhibitors.
