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Two modes of targeting transposable elements by piRNA pathway in human testis

Ildar Gainetdinov1, Yulia Skvortsova2, Sofia Kondratieva2

  • 1Department of Genomics and Postgenomic Technologies, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117997, Russia ildargv@gmail.com.

RNA (New York, N.Y.)
|August 27, 2017
PubMed
Summary

Human germline control of transposable elements (TEs) involves two piRNA production modes. Cluster-independent piRNAs target young TEs, while cluster-derived piRNAs target older TEs in postnatal spermatogenesis.

Keywords:
PIWI proteinspiRNA clusterpiRNA pathwaytransposable elements

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