Related Experiment Video

Updated: Feb 24, 2026

One-anastomosis Gastric Bypass OAGB in Rats
08:16

One-anastomosis Gastric Bypass OAGB in Rats

Published on: November 10, 2018

11.5K

The natural history of perforated marginal ulcers after gastric bypass surgery

Maria S Altieri1, Aurora Pryor2, Jie Yang3

  • 1Division of Bariatric, Foregut and Advanced Gastrointestinal Surgery, Department of Surgery, Stony Brook University Medical Center, 100 Nichols Road, HSC T19, Stony Brook, NY, 11794, USA. maria.altieri@stonybrookmedicine.edu.

Surgical Endoscopy
|August 27, 2017
PubMed
Abstract

Insights

Perforated marginal ulcers (pMU) after Roux-en-Y Gastric Bypass (RYGB) are rare but recurrence is common. Anastomotic revision for pMU leads to longer hospital stays than repair, with similar recurrence rates.

Area of Science:

  • Gastroenterology
  • Bariatric Surgery
  • Surgical Complications

Background:

  • Perforated marginal ulcers (pMU) are a serious complication following Roux-en-Y Gastric Bypass (RYGB).
  • The epidemiology and long-term outcomes of pMU after RYGB are not well-established.
  • Understanding these outcomes is crucial for managing this surgical emergency.

Purpose of the Study:

  • To determine the incidence of pMU in patients who underwent RYGB.
  • To assess the natural history and outcomes of pMU following RYGB.
  • To evaluate the effectiveness of different management strategies for pMU.

Main Methods:

  • Utilized the SPARCS administrative database to identify RYGB patients (2005-2010).
  • Tracked patients through 2014 for admissions related to pMU and subsequent interventions.
  • Employed statistical tests including Chi-square, t-test, and Wilcoxon rank-sum for group comparisons.

Main Results:

  • Identified 35,080 RYGB patients; 0.83% (292) developed pMU.
  • Tobacco use was noted in one-third of patients with pMU.
  • Anastomotic revision (64 patients) was linked to longer hospital stays and more respiratory complications compared to repair (115 patients).
  • Recurrence rates were high and similar for both repair (26.09%) and revision (29.69%).

Conclusions:

  • The incidence of pMU following RYGB is low.
  • Anastomotic revision for pMU is associated with increased hospital length of stay.
  • High recurrence rates suggest the potential benefit of routine surveillance programs for patients post-pMU intervention.
Keywords:
Perforated marginal ulcerRoux-en-Y Gastric Bypass

More Related Videos

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment03:32

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment

Published on: December 27, 2024

1.8K
Roux-en-Y Gastric Bypass Operation in Rats07:37

Roux-en-Y Gastric Bypass Operation in Rats

Published on: June 11, 2012

24.4K

Related Concept Videos

Peptic Ulcer Disease V: Surgical Management and Nursing Care01:25

Peptic Ulcer Disease V: Surgical Management and Nursing Care

Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
1.0K
Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
669
Peptic Ulcer Disease II: Pathophysiology01:28

Peptic Ulcer Disease II: Pathophysiology

Peptic Ulcer Disease (PUD) is characterized by the development of ulcers in the stomach or duodenal mucosa. Its pathophysiology is complex, involving a balance between damaging and protective elements.
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
2.3K
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
755
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
441
Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors01:24

Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors

Peptic ulcer disease, commonly called PUD, represents a multifaceted condition characterized by disruptions in the lining of the gastrointestinal (GI)  tract. Central to the protection of the gastrointestinal lining is the mucosal-bicarbonate barrier. This physiological defense mechanism is a formidable shield against the corrosive effects of gastric acid and pepsin secretion in the stomach. Its role is pivotal in maintaining the structural integrity of the stomach's inner lining.
1.3K