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Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

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Published on: February 5, 2018

Advances in rapid drug detection technology.

Wen-Bo Zou¹, Li-Hui Yin¹, Shao-Hong Jin¹

¹National Institutes for Food and Drug Control, China.

Journal of Pharmaceutical and Biomedical Analysis

|August 29, 2017

Summary

Counterfeit drugs (SFFC) pose a significant public health risk, particularly in developing nations. This review highlights rapid detection technologies and discusses emerging trends in SFFC drug characteristics and countermeasures.

Keywords:

Counterfeits Rapid detection SFFC drug

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Area of Science:

Analytical Chemistry
Pharmaceutical Sciences
Public Health

Background:

Spurious/Falsely-labeled/Falsified/Counterfeit (SFFC) drugs present a critical global health challenge.
These substandard medicines disproportionately affect rural populations in developing countries.

Purpose of the Study:

To review and summarize recent advancements in rapid detection technologies for SFFC drugs.
To discuss new trends in SFFC drug characteristics and potential solutions.

Main Methods:

Near Infrared Spectroscopy (NIRS)
Near Infrared Chemical Imaging (NIRCI)
Raman Spectroscopy
X-Ray Fluorescence (XRF)
X-Ray Powder Diffraction (XRPD)
Ion Mobility Spectrometry (IMS)
Ion Mobility Mass Spectrometry (IMMS)
Isotope Ratio Mass Spectrometry (IRMS)
Visual Analytical Methods

Main Results:

The review details the advantages of various rapid detection techniques.
Characterization examples of SFFC drugs using these technologies are provided.
Emerging characteristics and trends of SFFC drugs are identified.

Conclusions:

Rapid detection technologies are crucial for combating SFFC drugs.
Understanding SFFC drug trends is essential for developing effective countermeasures.
Technological advancements offer promising solutions to mitigate the SFFC drug threat.