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Vision

Vision

Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.

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Related Experiment Video

Updated: Feb 24, 2026

Using Looming Visual Stimuli to Evaluate Mouse Vision

Using Looming Visual Stimuli to Evaluate Mouse Vision

Published on: June 13, 2019

Functional Segregation and Development of Mouse Higher Visual Areas.

Tomonari Murakami^1,2, Teppei Matsui^3,2, Kenichi Ohki^1,2,4

¹Department of Molecular Physiology, Graduate School of Medical Sciences, Kyushu University, Maidashi, Higashi-ku, Fukuoka 812-8582, Japan, kohki@m.u-tokyo.ac.jp t-mura@m.u-tokyo.ac.jp.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience

|August 30, 2017

Summary

Higher visual areas (HVAs) in mice show functional segregation into ventral and dorsal streams, with the dorsal stream containing multiple substreams. This visual stream segregation develops gradually after eye opening in mice.

Keywords:

functional development functional segregation higher visual areas mouse visual cortex wide-field calcium imaging

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Area of Science:

Neuroscience
Visual processing
Mammalian visual cortex

Background:

Higher visual areas (HVAs) in mice are anatomically segregated into two streams, analogous to primate ventral and dorsal streams.
Functional characterization and developmental timing of HVAs in mice remain largely unknown.

Purpose of the Study:

To investigate the spatiotemporal selectivity of HVAs in adult and developing mice.
To determine the developmental timeline of functional segregation in mouse HVAs.

Main Methods:

Wide-field calcium imaging was employed to assess neuronal activity.
Spatiotemporal selectivity of nine HVAs was analyzed in adult and developing mice.

Main Results:

Lateral HVAs in the ventral stream exhibited similar spatiotemporal selectivity.
Anterior and medial HVAs in the dorsal stream showed non-uniform selectivity, indicating functional segregation into multiple substreams.
Functional segregation reached an adult-like pattern approximately 10 days after eye opening (EO).

Conclusions:

Mouse HVAs demonstrate functional segregation into ventral and dorsal streams, with the dorsal stream comprising multiple substreams for visuospatial processing.
Functional segregation of visual streams in mice develops gradually after eye opening.
Mouse HVAs serve as a valuable model for studying parallel visual processing and its developmental mechanisms.