Related Experiment Video
Updated: Feb 23, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Successful management of post-traumatic vancomycin-resistant enterococcus endophthalmitis
Jason Nguyen1, Mary Elizabeth Hartnett1
1John A. Moran Eye Center, 65 Mario Capecchi Dr, Salt Lake City, UT, USA.
Intravitreal amikacin successfully treated vancomycin-resistant enterococcal endophthalmitis 18 days post-trauma. This approach restored vision to 20/40, demonstrating its efficacy in challenging ocular infections.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Endophthalmitis is a severe intraocular infection.
- Vancomycin-resistant Enterococcus (VRE) poses a significant treatment challenge.
- Traumatic endophthalmitis requires prompt and effective management.
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