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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

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Invasive assessment of coronary artery disease

Stylianos A Pyxaras1, William Wijns2, Johan H C Reiber3

  • 1Cardiology Department, Coburg-Clinic, Ketschendorfer Str. 33, 96450, Coburg, Germany. steliospyxaras@gmail.com.

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
|August 30, 2017
PubMed

Insights

Accurate diagnosis of coronary artery disease during heart catheterization is crucial. Integrating anatomical and functional data improves prognostic stratification and guides treatment for better patient outcomes.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Interventional Cardiology

Background:

  • Coronary artery disease (CAD) presents significant mortality and morbidity.
  • Accurate diagnostic assessment during heart catheterization is vital for prognosis and treatment.
  • Intravascular imaging modalities complement coronary angiography for precise atherosclerotic burden quantification.

Purpose of the Study:

  • To review the current state-of-the-art invasive diagnostic methods used in heart catheterization.
  • To highlight the role of integrating anatomical and functional information in diagnosing coronary artery disease.

Main Methods:

  • Review of current invasive diagnostic techniques in heart catheterization.
  • Discussion of intravascular imaging modalities: intravascular ultrasound (IVUS) and optical coherence tomography (OCT).
  • Explanation of hemodynamic assessment using fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR).

Main Results:

  • Intravascular imaging allows precise quantification of atherosclerotic burden.
  • FFR and iFR serve as coronary flow surrogates to assess stenosis relevance.
  • Integration of anatomical and functional data offers a comprehensive approach.

Conclusions:

  • Invasive diagnostic methods during heart catheterization are essential for managing coronary artery disease.
  • Combining anatomical imaging with functional flow assessment enhances diagnostic accuracy.
  • Future strategies may leverage integrated data for improved percutaneous coronary intervention guidance.

Keywords:
Coronary angiographyfractional flow reserveintravascular ultrasoundoptical coherence tomography

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