Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...

Peripheral Artery Disease I: Introduction

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...

Atherosclerosis IV: Nursing Management

Atherosclerosis IV: Nursing Management

Nursing management for a patient with arteriosclerosis involves a comprehensive approach focusing on lifestyle modification, disease monitoring, education, and symptomatic care. Here is an overview of effective nursing strategies:Assessment and Monitoring: Initial and ongoing assessments are crucial. Nurses must document the patient's medical history, including any hypertension, diabetes, hyperlipidemia, and other cardiovascular diseases. Assessments also cover family history and lifestyle...

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Statewide Social Vulnerability Index (SVI) in Human Papillomavirus-Associated Oropharyngeal Squamous Cell Carcinoma.

American journal of clinical oncology·2025

Same author

Skin Cancer Awareness, Beliefs, Behaviors, and Access to Care Among the Homeless and Underinsured Patients Using a Free Clinic in Nebraska.

Cureus·2024

Same author

Dataset for gastrointestinal tract segmentation on serial MRIs for abdominal tumor radiotherapy.

Data in brief·2024

Same author

Modeling roadway impacts and recovery from volcanic ashfall from the 2021 St. Vincent eruption.

Journal of emergency management (Weston, Mass.)·2024

Same author

Coordinating science during an eruption: lessons from the 2020-2021 Kīlauea volcanic eruption.

Bulletin of volcanology·2023

Same author

The Impact of Internal Medicine Clerkship Characteristics and NBME Subject Exams on USMLE Step 2 Clinical Knowledge Exam Performance.

Journal of general internal medicine·2022

Search research articles

Related Experiment Video

Updated: Feb 23, 2026

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model

Published on: August 11, 2023

Takayasu arteritis presenting as embolic stroke.

Kristina Field¹, Laila Gharzai¹, Kaye Bardeloza¹

¹Department of Internal Medicine, Creighton University School of Medicine, Omaha, Nebraska, USA.

BMJ Case Reports

|August 31, 2017

Summary

This case highlights that patients with Takayasu arteritis may experience recurrent embolic strokes. Early screening for stroke sources is crucial, especially when symptoms reappear.

Keywords:

stroke vasculitis

More Related Videos

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli

Published on: September 25, 2016

Multimodality Diagnosis of Mesenteric Ischemia

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

Related Experiment Videos

Last Updated: Feb 23, 2026

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model

Published on: August 11, 2023

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli

Published on: September 25, 2016

Multimodality Diagnosis of Mesenteric Ischemia

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

Area of Science:

Vascular Neurology
Rheumatology
Cardiovascular Imaging

Background:

Takayasu arteritis is a rare, chronic inflammatory disease affecting large arteries, primarily the aorta and its branches.
Ischaemic stroke can be a presenting or a complication of Takayasu arteritis, often due to large artery stenosis or occlusion.
Tissue plasminogen activator is a critical treatment for acute ischaemic stroke, but secondary prevention strategies are vital.

Observation:

A 52-year-old woman presented with acute ischaemic stroke symptoms, successfully treated with tissue plasminogen activator.
Initial work-up revealed an aortic infiltrate consistent with early Takayasu arteritis.
The patient experienced recurrent stroke symptoms shortly after discharge, with newly identified intraluminal carotid artery clots.

Findings:

The recurrent ischaemic stroke was attributed to previously undetected intraluminal clots in the left common carotid and left internal carotid arteries.
Despite initial treatment for stroke and diagnosis of Takayasu arteritis, embolic events recurred rapidly.
This suggests that standard stroke work-up may miss embolic sources in the context of active vasculitis.

Implications:

Patients diagnosed with Takayasu arteritis require vigilant monitoring for embolic stroke, even after initial treatment.
Comprehensive screening for embolic sources, including intraluminal thrombi, is essential in Takayasu arteritis patients presenting with recurrent ischaemic events.
This case underscores the importance of considering vasculitis as a potential cause of embolic stroke and the need for tailored diagnostic and therapeutic approaches.