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Related Experiment Video

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Granulocyte-dependent Autoantibody-induced Skin Blistering
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Olanzapine-induced Skin Eruptions.

Nishtha Chawla1, Saurabh Kumar1, Yatan Pal Singh Balhara1,2,3,4

  • 1Department of Psychiatry, National Drug Dependence Treatment Centre (NDDTC), All India Institute of Medical Sciences (AIIMS), New Delhi, India.

Indian Journal of Psychological Medicine
|August 31, 2017
PubMed
Summary
This summary is machine-generated.

Olanzapine, a psychotropic medication, can cause fixed drug eruptions, a type of skin reaction. Early identification and discontinuation of olanzapine can improve patient outcomes and treatment adherence.

Keywords:
Antipsychotic agentsdrug eruptionsolanzapine

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Area of Science:

  • Psychiatry
  • Dermatology
  • Pharmacology

Background:

  • Adverse cutaneous reactions to psychotropic medications can impair drug compliance.
  • Literature on olanzapine-induced skin eruptions is limited compared to other psychotropics.

Observation:

  • A case of a 39-year-old male with first-episode mania and alcohol dependence syndrome is presented.
  • The patient developed fixed drug eruptions after initiating olanzapine treatment.

Findings:

  • Extensive investigations revealed no abnormalities.
  • Dermatological diagnosis confirmed fixed drug eruptions.
  • Skin eruptions resolved upon olanzapine discontinuation.

Implications:

  • Clinicians must recognize the potential for olanzapine-induced cutaneous reactions.
  • Timely detection and management of these eruptions are crucial for psychotropic treatment adherence.