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First report of postoperative intracranial Weeksella virosa infection

Sebastian M Toescu1, Sandra Lacey2, Hu Liang Low3

  • 1Department of Neurosurgery, Essex Neurosciences Centre, Queens Hospital, Romford, RM7 0AG, UK. s.m.toescu@gmail.com.

Acta Neurochirurgica
|August 31, 2017
PubMed

Insights

This study reports the first case of intracranial infection caused by Weeksella virosa, a bacterium typically found in the genitourinary tract. The patient successfully recovered after treatment with oral beta-lactam antibiotics.

Area of Science:

  • Neuroscience
  • Infectious Diseases
  • Microbiology

Background:

  • Malignant meningiomas (WHO grade III) can necessitate multiple craniotomies.
  • Recurrent tumors pose significant clinical challenges, increasing infection risk.

Observation:

  • A patient with recurrent malignant meningioma developed sepsis from a ventricular empyema.
  • Gram-negative rod, Weeksella virosa, was identified via 16S PCR in the debrided craniotomy wound.

Findings:

  • Weeksella virosa, usually a genitourinary commensal, caused a rare intracranial infection.
  • The infection was successfully treated with oral beta-lactam antibiotics.

Implications:

  • Highlights the potential for unusual pathogens in complex neurosurgical cases.
  • Demonstrates the efficacy of beta-lactam antibiotics for Weeksella virosa intracranial infections.
  • Emphasizes the importance of broad-spectrum identification in post-craniotomy sepsis.
Keywords:
Anaplastic meningiomaCentral nervous system infectionVentricular empyemaWeeksella virosa

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