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Direct Drug Delivery to Kidney via the Renal Artery
Published on: April 17, 2021
Enhancing clinical trial development for pediatric kidney diseases
H William Schnaper1, Joseph T Flynn2, Coleman Gross3
1Department of Pediatrics (Kidney Diseases), Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Abstract:
The conduct of clinical trials in small pediatric subspecialties such as pediatric nephrology is hampered by both clinical demands on the pediatric nephrologist and the small number of appropriate patients available for such studies. The American Society of Pediatric Nephrology Therapeutics Development Committee (TDC) was established to (1) identify the various stakeholders with interests and/or expertise related to clinical trials in children with kidney disease and (2) develop more effective partnerships among all parties regarding strategies for successful clinical trial development and execution. This article discusses the rationale, structure, and function of the TDC, the status of progress toward its goals, and the insights gained to date that may be useful for other subspecialties that face similar challenges.
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