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Capillary Electrophoresis: Instrumentation01:20

Capillary Electrophoresis: Instrumentation

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Capillary electrophoresis instrumentation typically consists of several key components. A high-voltage power supply generates the electric field necessary for the separation by connecting to an anode (the positively charged electrode) and a cathode (the negatively charged electrode) located in buffer reservoirs at each end of the capillary tube. The system includes a sample vial, a fused silica capillary tube coated with polyimide for mechanical strength through which the sample components...
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Related Experiment Video

Updated: Feb 23, 2026

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes
05:58

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes

Published on: March 22, 2022

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The Sysmex CS-5100 coagulation analyzer offers comparable analytical performance and excellent throughput

T Flieder1, T Gripp1, C Knabbe1

  • 1Institute for Laboratory and Transfusion Medicine, Heart and Diabetes Center, Ruhr University Bochum, Georgstrasse 11, 32545 Bad Oeynhausen, Germany.

Practical Laboratory Medicine
|September 1, 2017
PubMed
Summary

The Sysmex CS-5100 System is a robust, high-throughput blood coagulation analyzer. It demonstrates excellent analytical and operational performance, making it suitable for busy coagulation laboratories.

Keywords:
AutomationCS-5100Coagulation analyzerEvaluation

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Area of Science:

  • Clinical diagnostics
  • Hematology
  • Laboratory automation

Background:

  • Coagulation testing is crucial for diagnosing and managing bleeding and thrombotic disorders.
  • High-volume laboratories require efficient and reliable analyzers to meet demand.

Purpose of the Study:

  • To evaluate the analytical and operational performance of the Sysmex CS-5100 System.
  • To compare the CS-5100 with the Sysmex CS-2000i and ACL TOP 700 analyzers.

Main Methods:

  • Analytical performance comparison for routine, chromogenic, and immunological assays.
  • Imprecision, throughput, and STAT analysis studies.
  • Correlation analysis with patient samples.
  • Robustness and error rate assessment via stress testing.

Main Results:

  • Excellent correlation between Sysmex CS-5100 and Sysmex CS-2000i.
  • Impressive inter-assay precision (CV <3.5%) for CS systems.
  • CS-5100 processed 100 samples (210 results) in under 49 minutes.

Conclusions:

  • The Sysmex CS-5100 System is a robust, high-throughput analyzer.
  • It demonstrates excellent analytical and operational performance.
  • The CS-5100 is well-suited for demanding coagulation laboratory environments.