Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dyskeratosis Congenita with Pigmentary Mosaicism and Hematopoietic Trisomy 9 in a Female Associated with a de novo DKC1 Variant and Markedly Skewed X Chromosome Inactivation.

NPJ genomic medicineยท2026
Same author

Idiopathic pulmonary fibrosis risk loci in East Asian populations mirror those of European populations.

American journal of respiratory and critical care medicineยท2026
Same author

Myeloperoxidase promotes fibrosis by inhibiting cathepsin K to bias the lung toward ECM accumulation.

bioRxiv : the preprint server for biologyยท2026
Same author

Author Correction: Tissue-resident macrophage survival depends on mitochondrial function regulated by SerpinB2 in chronic inflammation.

Nature communicationsยท2026
Same author

Regulatory Effects of CD14<sup>+</sup>CD16<sup>++</sup>Slan<sup>+</sup> Monocytes on Classical Monocytes and T Lymphocytes in Response to Inflammatory and Phagocytic Stimuli.

Journal of immunology researchยท2026
Same author

SenSet defines cell-type specific senescence signatures in the aged human lung.

The EMBO journalยท2026

Related Experiment Video

Updated: Feb 23, 2026

Author Spotlight: Utilizing Next-Generation Polymerized Human Hemoglobin for Improved Donor Lung Evaluation and Preservation in Rats
09:47

Author Spotlight: Utilizing Next-Generation Polymerized Human Hemoglobin for Improved Donor Lung Evaluation and Preservation in Rats

Published on: June 14, 2024

1.2K

Ex Vivo Lung Perfusion: Past, Present, and Future.

Hannah C D'Cunha, Mauricio Rojas

    ASAIO Journal (American Society for Artificial Internal Organs : 1992)
    |September 1, 2017
    PubMed
    Summary

    Ex vivo lung perfusion (EVLP) offers a promising solution to the critical shortage of donor lungs for transplantation. This innovative technique reconditions unsuitable lungs, potentially saving lives for patients with end-stage lung disease.

    Area of Science:

    • Transplantation science
    • Regenerative medicine

    Background:

    • Lung transplantation is a life-saving treatment for end-stage lung diseases.
    • A significant shortage of suitable donor lungs limits transplantation, leading to patient mortality.

    Purpose of the Study:

    • To evaluate the potential of ex vivo lung perfusion (EVLP) in reconditioning donor lungs.
    • To assess EVLP's role in increasing the availability of lungs for transplantation.

    Main Methods:

    • Utilizing ex vivo lung perfusion (EVLP) technology to treat donor lungs.
    • Conducting clinical trials across multiple transplant centers worldwide.

    Main Results:

    • EVLP has demonstrated feasibility in reconditioning previously unsuitable donor lungs.

    More Related Videos

    Isolated Lung Perfusion System in the Rabbit Model
    10:18

    Isolated Lung Perfusion System in the Rabbit Model

    Published on: July 15, 2021

    4.1K
    Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death
    09:14

    Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death

    Published on: October 18, 2024

    1.1K

    Related Experiment Videos

    Last Updated: Feb 23, 2026

    Author Spotlight: Utilizing Next-Generation Polymerized Human Hemoglobin for Improved Donor Lung Evaluation and Preservation in Rats
    09:47

    Author Spotlight: Utilizing Next-Generation Polymerized Human Hemoglobin for Improved Donor Lung Evaluation and Preservation in Rats

    Published on: June 14, 2024

    1.2K
    Isolated Lung Perfusion System in the Rabbit Model
    10:18

    Isolated Lung Perfusion System in the Rabbit Model

    Published on: July 15, 2021

    4.1K
    Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death
    09:14

    Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death

    Published on: October 18, 2024

    1.1K
  • Clinical trials indicate EVLP's potential to expand the donor lung pool.

    • Conclusions:

    • Ex vivo lung perfusion (EVLP) is a viable technology for improving donor lung utilization.
    • EVLP shows promise in addressing the critical shortage of lungs for transplantation and reducing waiting list mortality.