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Updated: Feb 23, 2026

Handling Techniques to Reduce Stress in Mice
Published on: September 25, 2021
Effect of Canine Play Interventions as a Stress Reduction Strategy in College Students
Cheryl Delgado1, Margaret Toukonen, Corinne Wheeler
1Authors Affiliations: Associate Professor (Dr Delgado), Clinical Associate Professor (Dr Toukonen), and Associate Professor and Associate Dean (Dr Wheeler), Cleveland State University School of Nursing, Ohio.
Abstract:
Forty-eight students engaged with a therapy dog for 15 minutes during finals week to evaluate the effect on stress. Psychological (Perceived Stress Scale, visual analog scales) and physiologic stress (vital signs, salivary cortisol) measures were collected before and after the intervention. Paired t tests showed significant reductions in all psychological and physiologic measures except diastolic blood pressure. This supports animal-assisted therapy as an effective stress management strategy for nursing and other college students.
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