Related Experiment Video
Updated: Feb 23, 2026

An Orthotopic Resectional Mouse Model of Pancreatic Cancer
Published on: September 24, 2020
Ectopic pancreatic tissue in the wall of the small intestine: Two rare case reports
Jiannan Li1, Haibin Huang, Sibo Huo
1Department of General Surgery Department of Pathology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Insights
Ectopic pancreas, a rare congenital condition, can cause misdiagnosed abdominal symptoms. This study highlights two small intestine cases, emphasizing the need to consider ectopic pancreas in patients with unexplained intestinal masses.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Congenital Abnormalities
Background:
- Ectopic pancreas is a rare congenital anomaly that can occur anywhere in the gastrointestinal tract.
- It has a low incidence in the small intestine wall and often presents with atypical symptoms, leading to potential misdiagnosis.
Rationale:
Ectopic pancreas, which is a kind of rare congenital disease, forms during embryonic development. It can occur throughout the whole gastrointestinal tract, but has a low tendency to develop in the wall of the small intestine. It is easy for patients with ectopic pancreases to be misdiagnosed because the symptoms are untypical and can vary.
Patient Concerns:
In the present study, we reported two rare cases of ectopic pancreatic tissue in the wall of the small intestine, which presented with obvious abdominal pain and distention.
Diagnosis:
The laboratory tests and computed tomography (CT) scans didn't reveal any evidence of ectopic pancreas.
Interventions:
The two patients received small intestine masses resection and intestinal anastomosis.
Outcomes:
During surgery, an intestinal mass with a diameter of 4.0 cm was found in the first patient. An intestinal mass with a diameter of 0.8 cm, jejunum perforation, and diffuse peritonitis were found in the second patient. Histological analyses of the dissected intestinal masses confirmed them as ectopic pancreatic tissue. Interestingly, for the second patient, the intestinal perforation and diffuse peritonitis were not induced by the ectopic pancreas, but by a jujube pit that was found in the perforated site of the intestine.
Lessons:
Our study demonstrated that an ectopic pancreas should be considered in cases of untypical abdominal symptoms with intestinal masses.
More Related Videos
Related Concept Videos
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Histology of the Small Intestine
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
Renewal of Intestinal Stem Cells

