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Viscoelastic dynamic arterial response.
Haralambia P Charalambous1, Panayiotis C Roussis1, Antonios E Giannakopoulos2
1Department of Civil & Environmental Engineering, University of Cyprus, Nicosia, CY-1678, Cyprus.
Computers in Biology and Medicine
|September 1, 2017
Summary
Arterial viscoelasticity, crucial for arteries away from the heart, is simulated using a generalized Maxwell model. Results show relaxation time and pressure approximation significantly impact arterial response.
Area of Science:
- Biomechanics
- Biomaterials Science
- Computational Biology
Background:
- Arteries exhibit viscoelastic behavior, particularly those distal to the heart with higher smooth muscle content.
- Arterial mechanical response is influenced by topology and intraluminal pressure, leading to deformations and hysteresis.
- Viscoelasticity in arterial tissues is a key characteristic response investigated in this study.
Purpose of the Study:
- To investigate the viscoelastic response of arterial tissues.
- To understand the influence of material parameters on arterial viscoelasticity.
- To develop a numerical method for solving the governing integro-differential equation.
Main Methods:
- Simulated arterial wall viscosity using a generalized Maxwell model and internal variables.
- Modeled artery cross-section as a circular ring under time-varying blood pressure.
- Developed a novel numerical method to solve the viscoelasticity integro-differential equation.
Main Results:
- Numerical investigations revealed that the viscoelastic response is sensitive to the relaxation time to characteristic response time ratio.
- The pressure-time approximation was found to be a significant factor in the viscoelastic arterial response.
- Typical response time-profiles were generated and analyzed.
Conclusions:
- The study elucidates the impact of individual material parameters on viscoelastic arterial behavior.
- A deeper comprehension of viscoelastic artery mechanics has been achieved.
- The findings contribute to understanding arterial tissue mechanics.
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