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Reexpression of Prior Stroke Symptoms in Adults: When is a Mimic a Mimic?
James E Siegler1, Alexander J George, Sheryl Martin-Schild
1Department of Neurology, Tulane University School of Medicine, New Orleans, LA.
Abstract:
A "stroke mimic" refers to any clinical condition that causes neurological symptoms clinically indistinguishable from a cerebral lesion that affects a vascular distribution, but is not caused by ischemia. One subtype of stroke mimic, termed stroke reexpression, is a form of mimicry in which previously recovered or improved stroke symptoms recur in the setting of a neurological disturbance (seizure, hypoperfusion state) or a systemic disturbance (toxic, metabolic, infectious). Many reports of stroke reexpression exist in the literature and are well known to clinicians, but there has been no consensus regarding terminology that has been published to date. The purpose of this review is to summarize several examples of stroke reexpression and propose simple, useful criteria for this clinical condition.
Insights
Stroke mimics present symptoms similar to stroke but lack ischemia. Stroke reexpression is a subtype where prior stroke symptoms return due to other disturbances, lacking standardized terminology.
Area of Science:
- Neurology
- Clinical Neuroscience
Background:
- Stroke mimics are conditions with neurological symptoms resembling cerebral ischemia but without an ischemic cause.
- Stroke reexpression, a subtype, involves the recurrence of previous stroke symptoms due to non-ischemic triggers.
Observation:
- Clinical literature contains numerous reports of stroke reexpression.
- However, there is a lack of consensus on standardized terminology for this phenomenon.
Findings:
- This review synthesizes examples of stroke reexpression.
- It proposes practical criteria for identifying this condition.
Implications:
- Standardized criteria for stroke reexpression can improve clinical recognition and diagnosis.
- Clearer terminology may enhance communication and research in neurology.
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