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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
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Related Experiment Video

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Cervical Myelopathy Presenting as Bilateral Upper Extremity Weakness.

Sean McInerney, Aaron Keil, Jin Suh Kim

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    Summary

    Progressive upper extremity weakness in a 57-year-old man was diagnosed as cervical compressive myelopathy. Imaging revealed severe spinal stenosis and spondylosis, indicating the need for neurological evaluation.

    Keywords:
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    Area of Science:

    • Neurology
    • Orthopedics
    • Radiology

    Background:

    • A 57-year-old man presented with gradual onset of bilateral upper extremity weakness.
    • He was initially evaluated by his primary care physician and referred to physical therapy.

    Observation:

    • Physical therapy examination prompted a referral back to the primary care physician for further investigation.
    • The patient's symptoms suggested a potential neurological or spinal etiology.

    Findings:

    • Cervical radiographs showed degenerative changes at multiple levels.
    • Cervical spine magnetic resonance imaging (MRI) confirmed compressive myelopathy, significant spinal canal stenosis, and severe spondylosis.

    Implications:

    • These findings highlight the importance of recognizing subtle neurological signs in primary care.
    • Prompt imaging and specialist consultation are crucial for diagnosing conditions like cervical compressive myelopathy.
    • Early diagnosis and management can prevent further neurological deterioration and improve patient outcomes.