Related Experiment Video

Updated: Feb 23, 2026

Genome-wide Gene Deletions in Streptococcus sanguinis by High Throughput PCR
14:07

Genome-wide Gene Deletions in Streptococcus sanguinis by High Throughput PCR

Published on: November 23, 2012

17.0K

Whole-Genome Sequence of Streptococcus tigurinus Strain osk_001, Isolated from Postmortem Material

Hidenori Yoshizawa1,2,3,4, Daisuke Motooka5, Ryuichi Katada1,3

  • 1Department of Legal Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.

Genome Announcements
|September 2, 2017
PubMed

Insights

A novel bacterium, Streptococcus tigurinus, was identified in infected tissue. Whole-genome sequencing revealed unique genetic elements, confirming its high virulence and aiding in understanding severe infections.

Area of Science:

  • Microbiology
  • Genomics
  • Pathogen Research

Background:

  • Streptococcus tigurinus is a recently identified bacterial species.
  • Certain strains of S. tigurinus exhibit high virulence, posing a significant health concern.

Purpose of the Study:

  • To characterize and confirm the virulence of S. tigurinus.
  • To identify genetic factors contributing to the pathogenicity of S. tigurinus.

Main Methods:

  • Detection of S. tigurinus in infected tissue samples obtained during necropsy.
  • Whole-genome sequencing of a pure bacterial culture of S. tigurinus.

Main Results:

  • S. tigurinus was successfully detected and isolated from infected tissue.
  • Whole-genome sequencing identified specific and unique genetic elements within the S. tigurinus strain.
  • These genetic elements are associated with highly virulent strains of S. tigurinus.

Conclusions:

  • The study confirms the presence and virulence of S. tigurinus in clinical samples.
  • Unique genetic elements identified are crucial for understanding S. tigurinus pathogenicity.
  • Further research into these genetic elements may lead to targeted therapeutic strategies.

More Related Videos

Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing09:44

Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing

Published on: December 23, 2022

3.0K
Generating Whole Bacterial Genomes from Clinical Samples using a Target Enrichment Workflow10:44

Generating Whole Bacterial Genomes from Clinical Samples using a Target Enrichment Workflow

Published on: August 15, 2025

1.2K

Related Concept Videos

Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
759
Genomic DNA in Prokaryotes00:46

Genomic DNA in Prokaryotes

The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...
49.1K
Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
948