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Digitally Controlled Procedure for Assembling Fully Drawn Paper-Based Electroanalytical Platforms.

Nicolò Dossi1, Stefano Petrazzi1, Rosanna Toniolo1

  • 1Department of Agrifood, Environmental and Animal Science, University of Udine , via Cotonificio 108, I-33100 Udine, Italy.

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Summary
This summary is machine-generated.

A novel, low-cost method uses a plotter to create paper-based electrochemical devices (PEDs) for rapid analysis. This technique enables reproducible electrochemical sensing and vitamin B6 detection in supplements.

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Area of Science:

  • Electrochemistry
  • Materials Science
  • Analytical Chemistry

Background:

  • Paper-based electrochemical devices (PEDs) offer a low-cost, portable sensing platform.
  • Existing fabrication methods can be complex or expensive, limiting widespread adoption.
  • There is a need for simple, reproducible, and cost-effective methods for PED fabrication.

Purpose of the Study:

  • To propose a simple, reliable, and low-cost fabrication method for PEDs.
  • To utilize a commercial plotter and ordinary writing tools for device assembly.
  • To demonstrate the effectiveness of the fabricated PEDs for electrochemical analysis and real-world sample testing.

Main Methods:

  • Utilized a digital plotter/cutter with permanent markers for hydrophobic barriers and micromechanical pencils for carbon electrodes.
  • Optimized fabrication parameters including writing pressure and speed.
  • Evaluated electrochemical performance using potassium hexacyanoferrate(II) as a redox probe.

Main Results:

  • Achieved good interdevice reproducibility (4.8%) in voltammetric responses.
  • Demonstrated a low fabrication cost (approx. $0.04 per device) and rapid fabrication time (approx. 2 minutes).
  • Successfully utilized the fabricated PEDs for the analysis of vitamin B6 in food supplements.

Conclusions:

  • The proposed plotter-based fabrication method is a flexible, simple, and cost-effective approach for producing PEDs.
  • This method offers high reproducibility and is suitable for rapid prototyping and analysis of real samples.
  • The fabricated PEDs show promise for point-of-care diagnostics and field testing applications.