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Updated: Feb 23, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Editorial Commentary: Fixation of Soft-Tissue Anterior Cruciate Ligament Grafts in Osteoporotic Bone
1University of California, Los Angeles.
Abstract:
Tibial-side fixation of soft-tissue grafts in osteoporotic bone has become an important concern, as anterior cruciate ligament reconstruction indications push toward older patients. Although soft-tissue fixation with an interference screw and cortical button may be statistically stronger than graft fixation with a screw or button alone, this hybrid construct is probably not optimized from a clinical perspective.
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