Related Experiment Video
Updated: Feb 23, 2026
Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
Published on: September 15, 2023
Synchronous papillary thyroid carcinoma and medullary thyroid carcinoma - a pitfall waiting to happen
1Singapore General Hospital, Department of Anatomical Pathology, 20 College Road, Level 10, Diagnostics Tower, The Academia, Singapore. pyatang@gmail.com.
Abstract:
Papillary thyroid carcinoma (PTC) is the most common thyroid carcinoma and is derived from thyroid follicular cells. In contrast, medullary thyroid carcinoma (MTC) is rare and originates from the parafollicular C-cells. Synchronous occurrence of these two carcinomas is uncommon and occurs as either discrete lesions or as a mixed lesion. The current case report describes a 50-year-old woman with synchronous multiple discrete MTC and PTC with lymph nodes metastasis. Pathologists and treating physicians should be aware of the synchronous coexistence of these entities to avoid possible misdiagnosis.
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