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Updated: Feb 23, 2026

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Published on: January 23, 2026
Primary Cystic Pleuropulmonary Synovial Sarcoma Presenting as Recurrent Pneumothorax
Eric D Johnson1, Erinn Downs-Kelly2, David A Bull3
1Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Abstract:
Primary pleuropulmonary synovial sarcomas are quite rare, representing 0.1-0.5% of all pulmonary malignancies. We report an entirely cystic monophasic synovial sarcoma in a 25-year-old male who presented with recurrent pneumothorax and no evidence of a mass lesion on imaging. The purpose of this case report is to increase awareness of neoplasms clinically presenting as a pneumothorax with no imagining evidence of a mass-forming lesion and emphasize the significance of fluorescent in situ hybridization testing in nontypical synovial sarcoma cases.
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