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Updated: Feb 23, 2026

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
Ischemic Stroke in a Patient With Quadricuspid Aortic Valve and Patent Foramen Ovale
Michael Spartalis1, Eleni Tzatzaki1, Eleftherios Spartalis2
1Division of Cardiology, Onassis Cardiac Surgery Center, Athens, Greece.
Abstract:
Quadricuspid aortic valve (QAV) is a rare congenital aortic valve abnormality. It is less common as compared to bicuspid or unicuspid aortic valve abnormality. QAV causes aortic regurgitation usually in the fifth to sixth decade of life. We present a rare case of a female patient with cryptogenic stroke due to a QAV and a patent foramen ovale (PFO). The patient underwent transcatheter closure of PFO, as there was no clear indication for surgery for her valve. Surgical removal remains the method of choice for the treatment of the QAV before left ventricular decompensation occurs.
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