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Updated: Feb 23, 2026

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Malignant squamous cell carcinoma arising in a previously resected cerebellopontine angle epidermoid
Annika Mascarenhas1, Alyssa Parsons1, Caroline Smith2
1Department of Neurosurgery, Women's and Children's Hospital, North Adelaide, Australia.
Background:
Malignant squamous cell differentiation of an epidermoid cyst can carry a significantly poor prognosis and very little is known about this entity.
Case Description:
We present the case of a 35-year-old lady, with primary malignant squamous cell carcinoma (SCC) arising from a previously partially resected cerebellopontine angle epidermoid cyst almost 5 years after initial resection. We also review the relevant literature.
Conclusion:
The imaging findings, histopathology, and management of a malignant SCC arising from a benign epidermoid cyst are discussed with recommendation for increased surveillance and follow-up, even for classically accepted benign lesions.

