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Assessing Activity-based Anorexia in Mice
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THE ENDOCRINOPATHIES OF MALE ANOREXIA NERVOSA: CASE SERIES.

Aren Skolnick1, Rifka C Schulman1, Rodolfo J Galindo2

  • 1Division of Endocrinology and Metabolism, Hofstra Northwell School of Medicine, Long Island Jewish Medical Center, New Hyde Park, New York.

AACE Clinical Case Reports
|September 5, 2017
PubMed
Summary
This summary is machine-generated.

Anorexia nervosa (AN) in males is an overlooked cause of hormonal and systemic illness. Early diagnosis and nutritional support can resolve many complications, though hypogonadism may persist.

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Area of Science:

  • Endocrinology
  • Psychiatry
  • Internal Medicine

Background:

  • Anorexia nervosa (AN) is a serious eating disorder with significant morbidity and mortality, predominantly diagnosed in females.
  • Literature on AN in males is sparse, with limited focus on its endocrine consequences.
  • Male AN is an underrecognized cause of endocrinopathies and systemic illness in hospitalized patients.

Purpose of the Study:

  • To highlight the clinical characteristics of AN in males.
  • To underscore AN as a cause of multiple endocrinopathies and systemic illness.
  • To increase awareness of AN in the male population.

Main Methods:

  • A case series of 4 young men diagnosed with AN was reviewed.
  • Data were collected from chart reviews at two hospitals.
  • The study focused on hormonal dysfunction and systemic complications.

Main Results:

  • Four male patients exhibited systemic complications due to malnutrition, including hypogonadotropic hypogonadism, hypercortisolemia, and nonthyroidal illness syndrome.
  • Clinical manifestations included bradycardia, gastroparesis, hypothermia, heart failure, and erectile dysfunction.
  • Most symptoms resolved with nutritional rehabilitation, but hypogonadism symptoms persisted.

Conclusions:

  • AN is an important, often overlooked, cause of multiple endocrinopathies in males.
  • Heterogeneous presentations challenge diagnosis, emphasizing the need for increased awareness.
  • Prompt diagnosis and treatment of AN in males can improve metabolic dysfunction.