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New Trends in Inflammatory Bowel Disease.
Carolina Palmela1, Joana Torres1, Marilia Cravo1
1Gastroenterology Department, Surgical Department, Hospital Beatriz Ângelo, Loures, Portugal.
GE Portuguese Journal of Gastroenterology
|September 5, 2017
Summary
Inflammatory bowel disease (IBD) management is shifting towards proactive, aggressive strategies. New targeted therapies aim to achieve sustained remission and improve quality of life for patients with this progressive condition.
Area of Science:
- Gastroenterology
- Immunology
- Internal Medicine
Background:
- Inflammatory bowel disease (IBD) is a chronic gastrointestinal inflammatory condition.
- Historically, IBD treatment focused on symptom management, often overlooking disease progression.
- Recent advancements recognize IBD as a progressive disease causing significant bowel damage and disability.
Purpose of the Study:
- To outline the evolving treatment paradigm for IBD.
- To highlight the importance of early intervention and sustained inflammation control.
- To introduce new therapeutic agents and strategies for managing IBD.
Main Methods:
- Review of current clinical practices and treatment strategies for IBD.
- Discussion of newly approved targeted therapies, such as vedolizumab.
- Emphasis on a shift towards aggressive treatment for high-risk patients.
Main Results:
- A paradigm shift in IBD treatment towards proactive and stringent strategies.
- Incorporation of tailored therapy, mucosal healing, and sustained remission.
- Increased availability of novel therapeutic options for patients refractory to anti-tumour necrosis factor alpha (anti-TNFα) agents.
Conclusions:
- The future of IBD management is promising with new trends and drugs.
- These advancements aim to alter disease course, enhance therapy, and improve patient quality of life.
- Sustained control of inflammation and remission are key goals in modern IBD care.
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