Related Experiment Video
Updated: Feb 23, 2026

Subcellular Fractionation from Fresh and Frozen Gastrointestinal Specimens
Published on: July 15, 2018
Biopsies in Gastrointestinal Endoscopy: When and How.
Armando Peixoto1, Marco Silva1, Pedro Pereira1
1Gastroenterology Department, Centro Hospitalar de São João, Porto, Portugal.
This review examines when to perform endoscopic biopsies for gastrointestinal diseases. It aims to guide clinicians on rational resource use without compromising patient care during upper and lower endoscopy.
Area of Science:
- Gastroenterology
- Digestive System Diseases
- Medical Diagnostics
Background:
- Gastrointestinal endoscopy and biopsies are crucial for diagnosing digestive system diseases.
- Clinical practice often deviates from recommendations, leading to increased endoscopy requests and costs.
- Optimizing the use of endoscopic biopsies is essential for efficient healthcare.
Purpose of the Study:
- To review current evidence and guidelines on performing endoscopic biopsies in upper and lower endoscopy.
- To provide guidance on precise diagnosis of common gastrointestinal diseases.
- To promote rational resource utilization in endoscopic procedures.
Main Methods:
- Literature review of available evidence.
- Analysis of recent published guidelines.
- Focus on upper and lower endoscopy procedures.
- Consideration of common gastrointestinal diseases.
Main Results:
- Evidence and guidelines on the judicious use of endoscopic biopsies are presented.
- The review addresses specific gastrointestinal conditions motivating endoscopic examinations.
- Strategies for rational resource allocation are discussed.
Conclusions:
- Optimizing endoscopic biopsy practices is vital for accurate diagnosis and cost-effectiveness.
- Adherence to evidence-based guidelines can improve patient management.
- Rational use of resources in endoscopy is achievable without compromising patient care.
Related Concept Videos
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:
Endoscopic Procedures III: Video Capsule Endoscopy
Endoscopic Procedures II: Colonoscopy
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
Serum Laboratory Studies, Stool Test, Breath Test

