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The Immersive Cleveland Clinic Virtual Reality Shopping Platform for the Assessment of Instrumental Activities of Daily Living
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The Cleveland Clinic Rotodynamic Pump Program.

Leonard A R Golding1, William A Smith1, Douglas R Bodmann1

  • 1Department of Biomedical Engineering, The Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio, U.S.A.

Artificial Organs
|September 5, 2017
PubMed
Summary
This summary is machine-generated.

Cleveland Clinic developed a novel rotodynamic blood pump for permanent implantation. This compact, efficient device demonstrates low hemolysis and over 12 months of continuous function in endurance testing, paving the way for advanced ventricular assist systems.

Keywords:
Rotodynamic blood pump-Ventricular assist system

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Area of Science:

  • Biomedical Engineering
  • Cardiovascular Devices
  • Medical Implants

Background:

  • Development of advanced implantable blood pumps is crucial for treating end-stage heart failure.
  • Existing ventricular assist devices face challenges with power supply, control, and long-term reliability.

Purpose of the Study:

  • To introduce a novel rotodynamic blood pump designed for permanent cardiac implantation.
  • To detail the specifications, performance, and preliminary testing of this innovative blood pump.

Main Methods:

  • Design and development of a compact rotodynamic blood pump.
  • In vitro and in vivo testing to assess function, hemolysis, and reliability.
  • Integration with a transcutaneous electrical transmission system and pacer technology for control and telemetry.

Main Results:

  • The pump operates at 7 watts to deliver 5 L/min against 100 mm Hg at 3,000 rpm.
  • Initial in vivo tests confirmed in vitro performance with low levels of hemolysis.
  • Endurance testing demonstrated over 12 months of continuous, reliable function.

Conclusions:

  • The developed rotodynamic blood pump shows significant promise for permanent implantation as part of a ventricular assist system.
  • The integrated system, utilizing transcutaneous power and pacer technology, represents an innovative approach to cardiac support.
  • Further development and testing under an NHLBI contract are planned over the next five years.