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An explanation for the central to peripheral thickness variation in the mouse cornea.

Clinical & experimental ophthalmology·2011
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Size does matter: what is the corneo-limbal diameter?

Jan Pg Bergmanson1, Jesus G Martinez1

  • 1Texas Eye Research and Technology Center, University of Houston College of Optometry, Houston, Texas, USA.

Clinical & Experimental Optometry
|September 5, 2017
PubMed
Summary

Accurate corneal and limbal dimensions are crucial for scleral lens fitting. Current measurements are outdated and inaccurate, necessitating new protocols for precise corneo-limbal diameter determination.

Keywords:
corneal diametercorneo-limbal diameterhorizontal visible iris diameterlimbal widthscleral lens

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Area of Science:

  • Ophthalmology
  • Optometry
  • Biomedical Engineering

Background:

  • Accurate corneal and limbal dimensions are critical for fitting modern scleral lenses.
  • Existing published corneal diameter values are based on outdated, imprecise, and inconsistently defined measurements.
  • The widely cited average corneal diameter (11.7 x 10.6 mm) is derived from historical data and not direct measurement.

Purpose of the Study:

  • To review and critically assess available literature on corneal and limbal dimensions.
  • To highlight the limitations of current measurement techniques and definitions in ophthalmic literature.
  • To emphasize the need for standardized and accurate methods for determining corneo-limbal diameters.

Main Methods:

  • Systematic review of existing scientific literature concerning corneal and limbal measurements.
  • Analysis of measurement methodologies, definitions, and their historical context.
  • Evaluation of the accuracy and limitations of current ophthalmic instrumentation for these measurements.

Main Results:

  • Published corneal diameter values lack clear definitions and are often based on indirect or historical data.
  • Horizontal visible iris diameter measurements underestimate the true corneo-limbal diameter by excluding limbal width.
  • Current ophthalmic instrumentation may lack the necessary resolution and definition for precise corneo-limbal measurements.

Conclusions:

  • The limbal width remains structurally undefined and inaccurately measured in current literature.
  • There is a significant need for developing new protocols to accurately measure corneal and limbal dimensions.
  • More precise measurements are predicted to show that optimal scleral lens fitting requires diameters of 16.0 mm or larger.